Pregnancy is a very complex physiological process, must have all the conditions, in order to achieve the purpose of pregnancy. First, normal eggs and sperm are needed, followed by unimpeded reproductive tract, including the cervix, uterus, and fallopian tubes. The egg and sperm must be seen in the fallopian tube through the reproductive tract, or fertilization. The fertilized egg is like a seed that is transported from the fallopian tube to the uterus cavity and grown in the soft soil of the lining of the uterus. A new life was born.
Ovulation is an important part of the process. Women of childbearing age produce eggs every month. If the menstrual cycle is 28 days, the ovulation period of normal women is usually fourteenth to 16 days during the menstrual cycle. According to statistics, 10% of couples of childbearing age suffer from infertility, among whom female ovulation dysfunction accounts for 30% to 40%. Ovulation abnormality is the most common cause of infertility in women. The normal ovarian cycle is so complex that very small changes can break the normal cycle and inhibit ovulation. If women can’t produce eggs, there’s no way to get pregnant.
Development and ovulation of eggs
First of all, we should briefly understand the mechanism of ovulation. Establishment of normal ovulation cycle requires normal function of hypothalamus pituitary ovary axis. It is a complete and coordinated neuroendocrine system that regulates and influences each other, controlling female development, normal menstruation, and sexual functioning. The hypothalamus is like a command, the secretion of gonadotropin releasing hormone, which is ordered to the pituitary gonadotrophin secretion and ovarian gonadotropin received instruction after the secretion of estrogen and progestin induce follicular maturation and ovulation. Dysfunction or organic lesions of any part of the system can cause temporary or prolonged anovulation. According to statistics, in the ovulation disorders, thalamus dysfunction accounted for 38%, pituitary diseases accounted for 17%, ovarian dysfunction accounted for about 45%. Therefore, although ovulation disorders are different, the lesion location is different, the reasons are different, the treatment principle is also different.
Abnormal ovulation and its etiology
Ovulation abnormality is the inability to discharge normal eggs. Including complete absence of ovulation, rarely ovulation, or irregular ovulation. But there are still a few cases, after a thorough examination, there is still no explanation. The most common cause of abnormal ovulation is a lack of certain hormones. If the ovaries themselves are resistant to normal levels of hormones, they do not respond and can cause ovulation disorders. In addition, loss of ovary, damage, or disease can interfere with ovulation. There are many causes of ovulation abnormalities. The following are only a few common clinical diseases.
Ovarian dysfunction leading to anovulation is a common disease known as premature ovarian failure. In medicine, 40 year old premenopausal patients are called premature ovarian failure. Patients with early menstrual normal, and even have a history of fertility, but then menstruation is rare, until completely amenorrhea. The cause of the disease is unknown. This kind of patient’s ovarian follicles have been exhausted, it is impossible to use ovulation induction drugs to make follicular development, or even though the original follicle, but no response to gonadotropin. This kind of ovulation disorder patients, if you want to give birth, can only borrow someone else’s eggs as test tube baby, can achieve the purpose of pregnancy